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36px}.psp-coming-soon{width:300px;min-width:0;margin:0 auto 60px;background-color:#888;color:#fff;border-left:5px solid #31b571;box-shadow:inset 0 -4px 0 rgba(0,0,0,.25)}html[lang=fr] .psp-coming-soon{width:350px}.psp-intro{color:#0c1f37;text-align:center;font-size:1.625rem;font-weight:600;line-height:1.22;margin:0 0 28px}.psp-including,.psp-intro strong{font-weight:700}.psp-including{color:#0c1f37;font-size:1.25rem;line-height:1.2;margin:0 0 42px}.psp-services-grid{display:grid;grid-template-columns:repeat(3,1fr);gap:58px 74px;justify-items:center;align-items:start;margin:0 auto 66px}.psp-service-card{width:279px;min-height:330px;padding:52px 16px 42px;display:flex;flex-direction:column;justify-content:center;align-items:center;gap:28px;border-radius:200px;border:2px solid #fff;-tv-ignore: start E777;background:linear-gradient(223deg,#b4b9ff,#91cea3);-tv-ignore: end E777;color:#0c1f37;text-align:center}.psp-service-card 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#31b571;background:#0b5cd5;color:#fff;font-size:1rem;line-height:1;box-shadow:inset 0 -4px 0 rgba(0,0,0,.24)}.gate-btn-dark{background:#062844}.gate-btn:disabled{opacity:.65;cursor:not-allowed}.gate-arrow{text-align:center;color:#fff;font-size:4.5rem;line-height:1;margin:2.35rem 0 1.65rem}.gate-arrow svg{display:inline-block}.gate-video-title{color:#fff;text-align:center;font-size:1.875rem;font-style:normal;font-weight:500;line-height:120%;margin-bottom:40px}.gate-video-thumb{display:block;position:relative;width:100%;padding:0;border:0;border-radius:1rem;overflow:hidden;background:transparent;cursor:pointer}.gate-video-thumb>img{display:block;width:100%;height:auto}.gate-video-play{position:absolute;left:50%;top:50%;width:clamp(6rem,10vw,8.75rem);height:clamp(6rem,10vw,8.75rem);transform:translate(-50%,-50%);border-radius:50%;background:hsla(0,0%,100%,.82);display:flex;align-items:center;justify-content:center}.gate-video-play img{width:100%;height:100%}.gate-resource-copy{margin-top:4rem}.gate-resource-copy,.gate-resource-copy h2{color:#fff;text-align:center;font-size:1.875rem;font-style:normal;font-weight:500;line-height:120%}.gate-resource-copy h2{margin-top:40px}.gate-resource-copy p{color:#fff;margin-top:40px;font-size:1.5rem;font-style:normal;font-weight:500;line-height:120%}.gate-resource-grid{width:min(72%,52.125rem);margin:3rem auto 4rem;display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:clamp(2.5rem,5vw,4rem);align-items:start;justify-content:space-between}.gate-resource-card{position:relative;width:100%;padding:clamp(1.75rem,2.8vw,2.35rem) 1.25rem 1.5rem;border-radius:9px;-tv-ignore: start E777;background:linear-gradient(180deg,rgba(7,58,96,.72),rgba(7,44,83,.92)),url(/graphics/gate-resource-card-bg.png);-tv-ignore: end 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summary{position:relative;list-style:none;cursor:pointer;padding-right:34px;color:#2b5697;font-size:2.1875rem;font-style:normal;font-weight:600;line-height:125%;letter-spacing:.0625rem}.patient-faq-item summary::-webkit-details-marker{display:none}.patient-faq-item summary .faq-indicator{position:absolute;right:0;top:0;color:#2b5697;font-size:1.375rem;line-height:1}.faq-indicator .indicator-open,.patient-faq-item[open] .faq-indicator .indicator-closed{display:none}.patient-faq-item[open] .faq-indicator .indicator-open{display:inline}.patient-faq-item p{margin:10px 0 0;color:#000;font-size:1.875rem;font-style:normal;font-weight:400;line-height:125%;letter-spacing:.0625rem}.faq-table-card{background:hsla(0,0%,100%,.86);border-radius:12px;padding:24px 28px 28px;margin:16px 0;box-shadow:0 8px 22px rgba(43,86,151,.05)}.faq-table-item .faq-table-card{background:transparent;border-radius:0;padding:18px 0 0;margin:0;box-shadow:none}.faq-table-card h2{margin:0 0 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.faq-action-icon{font-style:normal;display:grid;width:22px;height:22px;border-radius:999px;place-items:center;background:#3fb777;color:#fff;font-size:.875rem;font-weight:800;line-height:1}.faq-ae-mobile-action strong{display:block;color:#2b5697;font-size:.875rem;line-height:1.2}.faq-ae-mobile-action span{display:block;margin-top:2px;color:#0c1f37;font-size:.875rem;line-height:1.25}.faq-side-effect-callout{width:min(1180px,100%);margin:22px auto 0!important;padding:16px 34px;border-radius:100px;-tv-ignore: start E777;background:linear-gradient(90deg,rgba(216,237,220,.75),rgba(191,232,249,.75));-tv-ignore: end E777;color:#2b5697!important;text-align:center;font-size:1.75rem!important;font-style:normal;font-weight:400!important;line-height:125%!important}@media (max-width:720px){.faq-gradient-title{font-size:3rem}.patient-faq-item{padding:16px 18px}.patient-faq-item summary{font-size:1.1875rem}.patient-faq-item p{font-size:1.0625rem}.faq-table-card{padding:20px 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rgba(43,86,151,.06)}.resources-intro{margin:0 0 58px;color:#0c1f37;font-size:clamp(1.5rem,2.7vw,2.25rem);font-weight:500;line-height:1.2}.resources-intro strong{color:#2b5697;font-weight:800}.resources-patient-grid{display:grid;grid-template-columns:1fr 1fr;gap:74px 108px;max-width:1000px;margin:60px auto 0}.resources-patient-item{display:grid;grid-template-columns:128px minmax(0,1fr);gap:24px;align-items:center}.resources-thumb{display:flex;align-items:center;justify-content:center;overflow:hidden;flex-shrink:0}.resources-thumb img{display:block;width:88%;height:88%;-o-object-fit:contain;object-fit:contain}.resources-item-copy h2{margin:0 0 14px;color:#000;font-size:1.5rem;font-style:normal;font-weight:500;line-height:120%}.resources-btn:disabled{padding-inline:12px}.resources-btn{width:210px;min-width:0;padding:10px 22px;text-transform:uppercase;color:var(--Official-Web-White,#fff);font-size:1rem;font-style:normal;font-weight:700;line-height:120%}.hcp-site .resources-btn{text-transform:none}@media (max-width:1200px){.resources-card{padding:40px 34px 48px}.resources-intro{font-size:1.5rem}.resources-patient-grid{grid-template-columns:1fr;gap:36px}}@media (max-width:640px){.patient-resources-page{padding-top:38px}.resources-gradient-title{font-size:3.4rem;margin-bottom:34px}.resources-card{padding:30px 22px 38px}.resources-intro{font-size:1.1875rem;margin-bottom:38px}.resources-patient-item{grid-template-columns:1fr;text-align:center}.resources-thumb{margin:0 auto}.resources-btn{width:100%}}.safety-page-wrap{padding:72px 20px 40px}.safety-page-card{max-width:1160px;margin:0 auto;background:#fff;border-radius:12px;box-shadow:0 26px 80px rgba(0,0,0,.26);padding:42px 48px 38px;color:#0c1f37}.safety-page-card h1{color:#0f4c9c;font-size:1.875rem;margin:0 0 22px}.safety-page-card h1,.safety-page-card h2{text-decoration:underline;font-family:var(--font-main,"elza","Elza Text",Arial,sans-serif);font-weight:700;line-height:1.3}.safety-page-card 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.patient-safety-copy{padding-left:0}.patient-safety-card-no-icon .patient-safety-copy h2{margin:0 0 8px;color:#2b5697;font-size:1.5rem;font-weight:800;line-height:1.15}.hcp-isi-page{padding:60px 32px 64px}.hcp-isi-container{width:min(100%,1310px);margin:0 auto}.hcp-isi-card{width:100%;padding:32px;border-radius:12px;background:#fff;color:#0c1f37}.hcp-isi-card h1{margin:0 0 24px;color:#0f4c9c;font-size:1.875rem;font-weight:700;line-height:1.25;letter-spacing:0}.hcp-isi-copy{font-weight:400}.hcp-isi-copy,.hcp-isi-copy h2{color:#0c1f37;font-size:1rem;line-height:1.625}.hcp-isi-copy h2{margin:0 0 20px;font-weight:700;text-decoration:underline}.hcp-isi-copy h2:not(:first-child){margin-top:20px}.hcp-isi-copy p{margin:0 0 20px}.hcp-isi-copy ul{margin:0 0 20px;padding-left:24px;list-style:disc}.hcp-isi-copy li{margin:0 0 8px;padding-left:2px}.hcp-isi-copy li:last-child{margin-bottom:0}.hcp-isi-copy li>ul{margin:8px 0 0;padding-left:24px}.hcp-isi-copy strong{font-weight:700}.hcp-isi-copy a{color:#0b5cd5;text-decoration:underline}.hcp-isi-reference{margin:56px 0 0;color:#fff;font-size:1rem;font-weight:400;line-height:1.625}.hcp-isi-reference strong{font-weight:700}@media (max-width:720px){.safety-gradient-title{font-size:3rem}.patient-safety-card{padding:16px 18px 18px}.patient-safety-heading-row{grid-template-columns:28px minmax(0,1fr);gap:10px}.patient-safety-icon{width:22px;height:22px}.patient-safety-icon img{width:20px;height:20px}.patient-safety-heading-row h2{font-size:1.25rem}.patient-safety-copy{padding-left:38px}.patient-safety-copy li,.patient-safety-copy p{font-size:.9375rem;line-height:1.3}.hcp-isi-page{padding:40px 20px 48px}.hcp-isi-card{padding:24px 18px}.hcp-isi-card h1{font-size:1.625rem;line-height:1.2}.hcp-isi-copy,.hcp-isi-copy h2,.hcp-isi-reference{font-size:.9375rem;line-height:1.55}}.gate-hero-top{display:grid;grid-template-columns:minmax(0,1fr) 470px;gap:clamp(3rem,7vw,7rem);align-items:start;margin-bottom:5.5rem}.gate-hero-top .gate-title{margin:0;width:510px;font-size:3.125rem;font-weight:600;line-height:1.12;letter-spacing:-.035em;justify-self:start}.gate-hero-top .gate-title sup{top:-1em;font-size:50%;line-height:0}.gate-video-cta{position:relative;display:flex;align-items:center;justify-content:space-between;gap:1.5rem;width:100%;min-height:106px;padding:1.625rem 1.5rem 1.625rem 2.6rem;border:0;border-radius:10px;overflow:hidden;-tv-ignore: start E777;background-image:linear-gradient(90deg,rgba(7,38,75,.66),rgba(0,168,130,.46)),url(/graphics/gate-video-cta-bg.png);-tv-ignore: end E777;background-size:100% 100%,cover;background-position:50%,50%;background-repeat:no-repeat;color:#fff;text-align:left;cursor:pointer;justify-self:end;align-self:start}.gate-video-cta span:first-child{position:relative;z-index:2;color:#fff;font-size:1.625rem;font-weight:600;line-height:1.15;white-space:nowrap}.gate-video-cta-play{position:relative;z-index:2;width:48px;height:48px;border-radius:999px;background:rgba(223,249,250,.96);display:flex;align-items:center;justify-content:center;flex:0 0 auto}.gate-video-cta-play img{display:block;width:100%;height:100%}.gate-forms{align-items:flex-start}.gate-card-hcp{overflow:visible}.gate-province-field{position:relative;z-index:5}.gate-custom-select-trigger{width:100%;display:flex;align-items:center;justify-content:space-between;min-height:48px;padding:0;border:0;border-bottom:2px solid rgba(132,185,255,.95);background:transparent;color:#dcecff;text-align:left;cursor:pointer}.gate-custom-select-trigger span{display:block;min-height:1.2em;color:#dcecff;font-size:1rem;font-weight:500;line-height:1.2}.gate-custom-select-arrow{color:#84b9ff;transition:transform .18s ease;flex:0 0 auto}.gate-custom-select-trigger.is-open .gate-custom-select-arrow{transform:rotate(180deg)}.gate-custom-select-panel{position:static;width:100%;margin-top:0;padding:0;background:transparent;border-bottom:3px solid #84b9ff;box-shadow:none}.gate-custom-select-option{display:block;width:100%;padding:11px 0;border:0;border-bottom:1px solid rgba(132,185,255,.82);background:transparent;color:#dcecff;text-align:left;font-size:1rem;font-weight:500;line-height:1.2;cursor:pointer}.gate-custom-select-option:focus,.gate-custom-select-option:hover{color:#fff;background:hsla(0,0%,100%,.08)}.din-modal{position:fixed;inset:0;z-index:9999;overflow-y:auto}.din-modal-overlay{position:fixed;inset:0;background:rgba(0,28,70,.78)}.din-modal-wrap{position:relative;min-height:100vh;display:flex;align-items:center;justify-content:center;padding:2rem}.din-modal-panel{position:relative;width:min(820px,calc(100vw - 2rem));border-radius:10px;background:#fff;padding:2.9rem 3.2rem 3.9rem;box-shadow:0 28px 80px rgba(0,0,0,.32);color:#0c1f37}.din-modal-close{position:absolute;top:1.45rem;right:1.45rem;width:28px;height:28px;padding:0;border:0;background:transparent;cursor:pointer;display:flex;align-items:center;justify-content:center}.din-modal-close img{display:block;width:24px;height:24px}.din-modal-title{color:#0f4c9c;font-size:1.875rem;font-style:normal;font-weight:700;line-height:54px;letter-spacing:-.025rem}.din-modal-copy{margin:0 0 2.25rem;color:#0c1f37;font-size:1rem;font-style:normal;font-weight:400;line-height:26px}.din-modal-image{display:block;width:min(640px,100%);height:auto;margin:0 auto}@media (max-width:991px){.gate-card-patient{height:auto}.gate-hero-top{grid-template-columns:1fr;gap:2.25rem;margin-bottom:3.75rem}.gate-hero-top .gate-title{max-width:720px}.gate-video-cta{max-width:520px;min-height:98px}.gate-video-cta span:first-child{font-size:1.375rem}.gate-video-cta-play{width:52px;height:52px}}@media (max-width:575px){.gate-hero-top .gate-title{font-size:3rem;line-height:1.12}.gate-video-cta{min-height:86px;padding:1.25rem 1.25rem 1.25rem 1.5rem}.gate-video-cta span:first-child{font-size:1.125rem}.gate-video-cta-play{width:44px;height:44px}.gate-video-cta-play img{width:18px;height:18px}.din-modal-wrap{padding:1rem}.din-modal-panel{padding:2.4rem 1.4rem 2rem}.din-modal-title{font-size:1.625rem}.din-modal-copy{font-size:.9375rem}.gate-page,body,html{width:100%;max-width:100%;overflow-x:hidden}.gate-shell{width:100%;max-width:100%;padding-left:1rem;padding-right:1rem}.gate-header{padding-top:1.5rem}.gate-logo{width:12rem;max-width:65vw}.gate-hero-top{display:block;margin-bottom:3rem}.gate-hero-top .gate-title{width:100%;max-width:100%;margin:0 0 2rem;font-size:2.65rem;line-height:1.1}.gate-video-cta{width:100%;max-width:100%;min-height:84px;padding:1.2rem 1.25rem}.gate-video-cta span:first-child{font-size:1.1rem;white-space:normal}.gate-video-cta-play{width:46px;height:46px;flex:0 0 46px}.gate-forms{display:block;width:100%;margin-top:0}.gate-card{width:100%;max-width:100%;min-height:0;padding:2rem 1.25rem;margin-bottom:2rem}.gate-card,.gate-card-patient{height:auto}.gate-professions{grid-template-columns:repeat(2,minmax(0,1fr));gap:.75rem 1rem}.gate-professions label{white-space:normal}.gate-arrow{margin:2.75rem 0}.gate-video-title{margin-bottom:1.75rem;font-size:2rem;line-height:1.15}.gate-video-thumb{width:100%;max-width:100%}.gate-resource-copy{margin-top:3rem}.gate-resource-copy h2{margin-top:0;font-size:1.75rem}.gate-resource-copy p{margin-top:1.75rem;font-size:1.35rem}.gate-resource-grid{width:100%;max-width:100%;grid-template-columns:1fr;gap:1.75rem;margin:2.5rem auto 3rem}.gate-resource-card,html[lang=fr] .gate-resource-card{width:100%;min-height:0;height:auto;aspect-ratio:auto;padding:2rem 1.5rem;overflow:visible}.gate-resource-card img{width:110px;height:110px;margin-bottom:1.5rem}.gate-resource-card span,html[lang=fr] .gate-resource-card span{font-size:1.4rem;line-height:1.2}.site-footer{width:100%;max-width:100%;padding:2rem 1.25rem}.site-footer-inner{width:100%;max-width:100%;grid-template-columns:1fr;gap:1.5rem}.site-footer-links{text-align:left}}.cookie-alert{width:100%;max-width:100%;margin:0;overflow:hidden}.cookie-alert>div{padding-left:1.25rem;padding-right:1.25rem;box-sizing:border-box}.cookie-alert-inner,.cookie-alert>div{width:100%;max-width:55rem;margin:0 auto}.cookie-alert-inner{display:flex;align-items:center;gap:2rem;padding:1.25rem}@media (max-width:767px){.cookie-alert-inner{display:block}.cookie-alert-inner p{margin-bottom:1rem}.cookie-alert-inner button{width:100%}.cookie-alert>div{display:block;padding:1rem}.cookie-alert p{margin:0 0 1rem;font-size:.875rem;line-height:1.4}.cookie-alert button{display:block;width:100%;white-space:normal}}@media (max-width:1200px){.patient-card-administering{background-image:url()}.patient-header-inner{max-width:1180px}.patient-main-menu{gap:clamp(18px,3vw,42px)}.patient-container,.patient-footer-inner{max-width:1180px}}.skip-link:focus{position:fixed;top:1rem;left:1rem;z-index:10000;width:auto;height:auto;margin:0;padding:.75rem 1rem;overflow:visible;clip:auto;white-space:normal;background:#fff;color:#001f63;outline:2px solid currentColor}[class~="*:whitespace-nowrap"]>*{white-space:nowrap}@media (min-width:480px){[class~="xs:text-lg"]{font-size:1.125rem;line-height:1.2}}@media (min-width:768px){[class~="md:mt-0"]{margin-top:0}[class~="md:flex"]{display:flex}[class~="md:gap-14"]{gap:3.5rem}[class~="md:px-11"]{padding-left:2.75rem;padding-right:2.75rem}}